Artificial intelligence (AI) is booming. Various AI algorithms are used in many scientific domains, corresponding to to foretell the construction of proteins, seek for supplies with specific properties, and interpret medical information to supply a prognosis. People use instruments like ChatGPT, Claude, NotebookLM, DALL-E, Gemini, and Midjourney to generate photos and movies from textual content prompts, write textual content, and search the internet.
The query arises in the identical vein: can they show helpful in research of the elementary properties of nature or is there a niche between human and synthetic scientists that must be bridged first?
There is actually some hole. Many of the present functions of AI in scientific analysis typically use AI fashions as a black field: when the fashions are skilled on some information they usually produce an output, however the relationship between the inputs and the output isn’t clear.
This is taken into account unacceptable by the scientific neighborhood. Last yr, for instance, DeepMind confronted strain from the life sciences neighborhood to launch an inspectable model of its AlphaFold mannequin that predicts protein constructions.

The black-box nature presents the same concern in the bodily sciences, the place the steps main as much as an answer are as essential as the resolution itself. Yet this hasn’t dissuaded scientists from attempting. In reality, they began early: since the mid-Nineteen Eighties, they’ve built-in AI-based instruments in the research of advanced techniques. In 1990, high-energy physics joined the fold.
Astro- and high-energy physics
In astronomy and astrophysics, scientists research the construction and dynamics of celestial objects. Big-Data analytics and picture enhancement are two main duties for researchers in this area. AI-based algorithms assist with the first by in search of patterns, anomalies, and correlations.
Indeed, AI has revolutionised astrophysical observations by automating duties like capturing photos and monitoring distant stars and galaxies. AI algorithms are in a position to compensate for the earth’s rotation and atmospheric disturbances, producing higher observations in a shorter span. They are additionally in a position to ‘automate’ telescopes which are in search of very short-lived occasions in the sky and report essential data in actual time.
Experimental high-energy physicists typically take care of giant datasets. For instance, the Large Hadron Collider experiment in Europe generates greater than 30 petabytes of information yearly. A detector on the collider referred to as the Compact Muon Solenoid alone captures 40 million 3D photos of particle collisions each second. It could be very troublesome for physicists to analyse such information volumes quickly sufficient to trace subatomic occasions of curiosity.
So in one measure, researchers at the collider began utilizing an AI mannequin in a position to precisely establish a particle of curiosity in very noisy information. Such a mannequin helped uncover the Higgs boson particle over a decade in the past.

AI in statistical physics
Statistical mechanics is the research of how a bunch of particles behaves collectively, reasonably than individually. It is used to know macroscopic properties like temperature, and strain.
For instance, Ernst Ising developed a statistical mannequin for magnetism in the Twenties, specializing in the collective behaviour of atomic spins interacting with their neighbours. In this mannequin, there are greater and decrease vitality states for the system, and the materials is extra prone to exist in the lowest vitality state.
The Boltzmann distribution is a crucial idea in statistical mechanics, used to foretell, say, the exact circumstances in which ice will flip to water. Using this distribution, in the Twenties, Ernst Ising and Wilhelm Lenz predicted the temperature at which a cloth changed to non-magnetic from magnetic.
Last yr’s physics Nobel laureates John Hopefield and Geoffrey Hinton developed a idea of neural networks in the identical manner, primarily based on the thought of statistical mechanics. An NN is a sort of mannequin the place nodes that may obtain information to carry out computations on them are linked to one another in other ways. Overall, NNs course of data the manner animal brains do.
For instance, think about a picture made up of pixels, the place some are seen and the relaxation are hidden. To decide what the picture is, physicists have to think about all attainable methods the hidden pixels may match along with the seen items. The thought of most certainly states of statistical mechanics may assist them in this situation.
Hopefield and Hinton developed a idea for NNs that thought-about the collective interactions of pixels as neurons, identical to Lenz and Ising earlier than them. A Hopfield community calculates the vitality of a picture by figuring out the least-energy association of hidden pixels, much like statistical physics.
AI instruments apparently returned the favour by serving to make advances in the research of Bose-Einstein condensates (BEC). A BEC is a peculiar state of matter {that a} assortment of sure subatomic or atomic particles have been recognized to enter at very low temperatures. Scientists have been creating it in the lab since the early Nineties.
In 2016, scientists at Australian National University tried to take action utilizing AI’s assist with creating the proper circumstances for a BEC to type. They discovered that it did so with flying colors. The instrument was even in a position to assist hold the circumstances secure, permitting the BEC to last more.
“I didn’t expect the machine could learn to do the experiment itself, from scratch, in under an hour,” the paper’s coauthor Paul Wigley stated in an announcement. “A simple computer program would have taken longer than the age of the universe to run through all the combinations and work this out.”

Bringing AI to the quantum
In a 2022 paper, scientists from Australia, Canada, and Germany reported a less complicated methodology to entangle two subatomic particles utilizing AI. Quantum computing and quantum applied sciences are of nice analysis and sensible curiosity right now, with governments — together with India’s — investing hundreds of thousands of {dollars} in creating these futuristic applied sciences. A giant a part of their revolutionary energy comes from attaining quantum entanglement.
For instance, quantum computer systems have a course of referred to as entanglement swapping: the place two particles which have by no means interacted turn into entangled utilizing intermediate entangled particles. In the 2022 paper, the scientists reported a instrument referred to as PyTheus, “a highly-efficient, open-source digital discovery framework … which can employ a wide range of experimental devices from modern quantum labs” to higher obtain entanglement in quantum-optic experiments.
Among different outcomes, scientists have used PyTheus to make a breakthrough with implications for quantum networks used to securely transmit messages, making these applied sciences extra possible. More work, together with analysis, stays to be performed however instruments like PyTheus have demonstrated a possible to make it extra environment friendly.
From this vantage level in time, it looks like each subfield of physics will quickly use AI and ML to assist remedy their hardest issues. The finish objective is to make it simpler to provide you with the extra applicable questions, take a look at hypotheses quicker, and perceive outcomes extra gainfully. The subsequent groundbreaking discovery might properly come from collaborations between human creativity and machine energy.
Shamim Haque Mondal is a researcher in the Physics Division, State Forensic Science Laboratory, Kolkata.
Published – June 08, 2025 03:05 pm IST






